Longitudinal immune profiling reveals distinct features of COVID-19 pathogenesis

Elizabeth Mann and Madhvi Menon will discuss findings from their recent longitudinal immune profiling study with admitted COVID-19 patients across four hospitals in Manchester at the height of the pandemic in the UK. They find key immune signatures that track with disease severity and can potentially be used to identify patients upon admission that are destined for intensive care. They also determine how immune responses change throughout the disease course and how this differs in patients with milder disease that recover compared with patients who go on to become severe/critical.

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