Becas y oportunidades de trabajo
Becas ayuda económica para concurrir a:
ALACI 2022 del 6-10 de junio en Varadero, CUBA
A funded postdoctoral fellow position is available in the Battistone laboratory at
Massachusetts General Hospital and Harvard Medical School to explore the
molecular basis of mucosal immunity in the urogenital tract, with the aim to
identify new diagnostic/therapeutic targets for kidney injury and male infertility.
We employ an innovative multidisciplinary approach that makes use of different
state-of-the-art techniques including 3D confocal microscopy, transcriptomics
analysis, flow cytometry and cell sorting, as well as mouse models to describe how
specialized epithelial cells and immunocytes communicate in the urogenital tract.
Postdoctoral fellows will benefit from a highly collaborative environment and
connections to premier biomedical institutions in the greater Boston area
Candidates for this position must have a Ph.D. in the biomedical sciences. Ideal
applicants will have an experimental background in molecular/cellular biology and
mouse models of disease, a strong publication record, and excellent
If interested, please email a cover letter, CV, and the contact information for three
Maria Agustina Battistone
Massachusetts General Hospital
Harvard Medical School
IN ANTI-VIRAL INNATE IMMUNITY
Location: INSERM U932, Institut Curie, Paris, France
Date posted: JULY 2021
Application deadline: SEPTEMBER 2021
Job description summary
The research group of Dr Philippe Benaroch (http://ow.ly/WjoV50yVbOQ) is seeking a PhD-qualified scientist. The candidate will join the ongoing project which aims at further developing a human adoptive cell therapy platform to treat solid tumors based on genetic engineering of primary myeloid cells. The candidate will be in charge of designing and performing preclinical in vivo experiments with immunodeficient mice carrying human tumors.
The Benaroch’s team is part of a 130-person Immunology department (Inserm U932, Paris, France) headed by Dr Anna-Maria Lennon at Institut Curie. The team is focused on myeloid cells that represent a very ancient form of cellular immunity against pathogens and tumor cells. They are very plastic, endowed with an ever-growing list of functions in innate and adaptive immunity. How myeloid cells crosstalk with viruses and tumor cells, and how this interplay is regulated remain to be established at the molecular level and represent the focus of his lab. The team offers the opportunity to expand and develop your career in the exciting professional environment of Institut Curie promoted by an open culture and a spirit of community. Institut Curie is one of the largest European institutions for cancer and biomedical research with strong interdisciplinary traditions. It is equipped with state-of-the-art facilities (imaging, proteomic, animal facility, genomic and cytometry platforms).
Solid cancers are shaped by a complex tumor microenvironment (TME) that critically impacts their growth and metastatic potential, as well as their response to therapies. Myeloid cells shape the TME and are major players in immune resistance and/or evasion mechanisms. Myeloid cells have a great capacity to phagocytose dead and even living cells, including tumor cells. This activity is coupled to their antigen presentation function which can stimulate the adaptive immune response. Harnessing their plasticity and functional properties, we aim to use myeloid cells as anti-tumor therapeutic agents following their genetic engineering. This should stimulate the anti-tumor response and counteract the immunosuppressive activity of myeloid cells in the TME. By combining state-of-the-art
technologies in molecular biology and cell biology with in vivo experimental approaches, we plan to reinforce our preliminary results and develop optimized myeloid cells as anti-cancer adoptive cell therapy.
• PhD in Immunology, experience with mouse models (i.v tail injections, harvesting lymphoid organs, training in animal experimentation) and with multicolor FACS analyses
• Some knowledge in cancer biology and cell biology is not mandatory but will be highly appreciated
Desirable Knowledge, skills and abilities:
• Scientific rigor and excellent analytical and synthetic capabilities
• Team spirit, and dynamic personality with passion for innovation and problem-solving
18 months already funded with possible extension.
Please send CV and two letters of reference to email@example.com AND TO firstname.lastname@example.org
RESEARCH ENGINEER IN IMMUNOLOGY
Open position: Research engineer with a PhD and experience in immunology
Location: U932, Team TransImm, Institut Curie, Paris, France
Date posted: July 2021
Application deadline: October 2021
The research group of Dr. Eliane Piaggio (Inserm U932, Paris, France) is seeking a degree-qualified research engineer. The research engineer will be dedicated to work on several projects in the frame of fundamental and translational immunology research studying different immunotherapeutic approaches in mouse preclinical models, mainly in humanized NSG mouse models. The applicant will be in charge of developing, handling, analyzing the experiments and follow the bibliography.
The initial contract is for 3 years.
Projects will be developed under the supervision of Dr Eliane Piaggio leading the team “Translational Immunotherapy” (https://science.curie.fr/recherche/biologie-interactive-des-tumeurs-immunologie-environnement/immunite-et-cancer/equipe-piaggio-loirat/) and Dr Christine Sedlik, senior research engineer.
The team encompasses 10 members, including two bioinformaticians and a project manager.
The group is part of a 130-person immunology department headed by Anna-Maria Lennon. The lab is located within the Institut Curie campus in the center of Paris. The building is equipped with state of the art facilities (imaging, proteomic, animal facility, genomic and cytometry platforms). The Institute hosts around 1500 bench scientists including many foreign students and post-doctoral fellows.
- PhD in immunology and demonstrated success in a previous research experience in immunology testified by publications
- Experience in humanized NSG mice would be appreciated
Technical skills and abilities:
- Expert in mouse experimentation (1st/2nd level of authorization)
- Expert in multiparametric FACS
- Cell culture, ELISA, ELISPOT…
- Strong motivation, autonomy and excellent team working skills
- High standards of integrity, accuracy and great rigor are essential
- Good proficiency in English is mandatory
Please send CV and motivation letter to email@example.com