Webinar: Ramos B cell engineering for the evaluation of the humoral anti-SARS-CoV-2 immunity

Michael Reth and his team are studying how the B cell antigen receptor (BCR) and the B cell surface is organized in resting and activated B cells for the sensing of foreign antigens. They learned that the BCR and many B cell surface markers are highly organized at nanoscale distances. In their studies they are […]

Webinar: Prevention and Therapy of COVID-19 with Monoclonal Antibodies

Hans-Martin Jäck summarizes the COVID-19 pandemic and CoV-2-host cell interactions. He introduces the concept of passive immunisation and active vaccination to prevent and protect from COVID-19, and he provides an overview of the current clinical serum and vaccine trials, finishing the webinar with a review on the production of human CoV-2 neutralising antibodies in transgenic […]

Webinar: Seeking correlates of protection and correlates of pathology in COVID-19 patients

In this webinar, Professor Adrian Hayday will share with us, an overview of a completed deep immunophenotyping of 100 patients and controls, with approximately 200,000 data points. Professor Adrian Hayday began studying immunology in 1982 at MIT, where he and his colleagues first described the wholly unanticipated T-cell receptor gamma chain genes. Establishing that γδ […]

Webinar: Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis

Eric Vivier provides a longitudinal analysis of immune responses, including immune cell phenotyping and assessments of the soluble factors present in the blood and broncho-alveolar lavage fluid (BALF) of patients at various stages of COVID-19 severity: paucisymptomatic, pneumonia and acute respiratory distress syndrome (ARDS). He reports an increase in soluble C5a levels proportional to COVID-19 […]

Webinar: COVID-19 in South Africa

Since the first case of COVID-19 on 5 March 2020 in South Africa, the epidemic grew exponentially with a doubling time of 2 days for the first 3 weeks until the effects of state-initiated interventions impacted reducing the doubling time to 15 days. The National response, which comprises 8 stages aims to flatten the curve. […]